Cervical cancer during pregnancy is rare and difficult to diagnose and treat. Accurate identification of the extent of cancer is more difficult during pregnancy because induration of the base of the broad ligaments, which in nonpregnant women
characterizes tumor spread beyond the cervix, may be less prominent during pregnancy. If careful study of the cervix by cytology, colposcopy, and directed biopsy and occasionally by cone biopsy indicates that the disease is intraepithelial, the
pregnancy may be allowed to go to term with normal vaginal delivery, and treatment deferred until the postpartum period. For more advanced cancer, the disease should be treated without regard to the pregnancy unless the pregnancy is 24 weeks or
more.
After 28~32 weeks, the baby can be delivered by classical cesarean section and treatment then instituted.
Glassy cell carcinoma is a poorly differentiated carcinoma characterized by sheets of cells having 1) a moderate amount of cytoplasm with a ground-glass or granular appearance, 2) a distinct cytoplasmic membrane, and 3) a large nucleus containing
prominent single or multiple nucleoli. Therapy is the same as for invasive squamous cell carcinoma and adenocarcinoma of the same stage, but the prognosis is not as good.
We report a case of glassy cell carcinoma of the cervix during pregnancy.
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